Mast cells can be inhibited by palmitoylethanolamide, relevance for IC/ CBS


Chronic Bladder Syndrome can be treated with PEA 1200 – 2400 mg/day; this brings the mast cells to rest.

Interstitial Cystitis or chronic bladder syndrome (or bladder pain syndrome) is associated with a number of symptomatic sequelae that are poorly understood on a mechanistic level. The current study provides evidence suggesting that MCP-1-induced increases in histamine release are associated with CCR2 surface proteins on Mast Cells and are involved in the development and progression of IC/BPS.

More info on chronic bladder pain and its treatment

Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

%d bloggers like this: