The chairman and secretary of the IOCOB, together with the well-known American pain specialist dr. Nancy Sjalben, have published a new treatment for severe unexplained vaginal pains in the Archives of Gynecology and obstetrics, the international classic journal for female specific conditions. The title of the article is:
Vulvodynia and proctodynia treated with topical baclofen 5 % and palmitoylethanolamide. The summary of the article clearly shows the essence: 
A 33-year-old woman with intractable chronic vulvar and anal pain had to abstain from sexual intercourse and could neither cycle nor sit for more than 5 min. The patient did not respond to standard treatments. We prescribed a combination of topical baclofen 5 % and palmitoylethanolamide 400 mg, three times daily. After 3 months her symptoms decreased more than 50 % and sexual intercourse was possible again without pain.
Unexplained vaginal pain is more common than we think. It concerns about 5-10% of all women. Treatment of this condition can be tricky. In the article a successful treatment is discussed, based on the natural pain relief substance palmitoylethanolamide and a topical pain relieving cream containing baclofen. The patient was able to have sexual intercourse again for the first time in years. The pain decreased considerably and she was able to sit again.
Using natural substances like palmitoylethanolamide (available as a PEA supplement PeaPure or PEA cream), which have no patented rights anymore, doctors can often successfully treat these difficult vaginal conditions with effective topical creams.
This patient is not the only one. Fortunately specialized pelvic physiotherapists are now also becoming familiar with these types of treatments, which are a break-through in the treatment of these tricky vaginal conditions.
 Keppel Hesselink JM1, Kopsky DJ, Sajben NL. | Vulvodynia and proctodynia treated with topical baclofen 5 % and palmitoylethanolamide. | Arch Gynecol Obstet. | 2014 Apr 2. [Epub ahead of print]