Palmitoylethanolamide: mechanism against infections, enhancement of resistance against bacteria

“Palmitoylethanolamide increases the resistance against infections”

is the keymessage of a new article which highlights one of the positive medical aspects of the treatment with palmitoylethanolamide in inflammations: PEA enhances the immunesystem in its fight against bacteria. It can do so, without having negative effects on white blood cells, such as overactive stimulation.

The authors concluded:

Our observations suggest that these protective effects of PEA in mice can increase the resistance to bacterial infections without the hazard of collateral damage by excessive stimulation of phagocytes.

This is a very important article, as it is one of the more recent articles underlining old observations from decades ago, were PEA was found to be an anti-inflammatrory agent. Now, after having discovered the mechanism of action of PEA in the treatment of pain, its natural properties to enhance our immune system and help our defense against infections becoming more and more known.

Therefore PEA seems indeed a very appropriate therapy in all kinds of chronic inflammations.

Source:
Redlich S, Ribes S, Schütze S, Nau R. Palmitoylethanolamide stimulates phagocytosis of Escherichia coli K1 by macrophages and increases the resistance of mice against infections. J Neuroinflammation. 2014 Jun 14;11(1):108.

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