Post Traumatic Stress Disorder: chronic decrease of PEA, OEA and related lipids

Follow2Autacoid Medicine is starting to get recognized as a new way to treat using natural and endogenous compounds, the autacoids. PEA is such an autacoid.

German scientists compared the concentration of PEA-related lipids, the N-acylethanolamides in hair of PTSD patients and compared these to healthy normal people. Quite impressive strong negative relationships between all investigated N-acyl-ethanolamides and symptom severity of PTSD was found.


Angst and PTSD treated with natural compound PEA

The authors concluded that their findings add to the accumulating evidence suggesting these lipid autacoids are a target for pharmacological enhancement of exposure-based psychotherapy for PTSD.

This also adds to the experiences that PEA can be used to boost many different interventions: treatment with opioids, NSAIDs, ketamine, all kinds of co-analgesics and related compounds.

Source:Wilker S, Pfeiffer A, Elbert T, Ovuga E, Karabatsiakis A, Krumbholz A, Thieme D, Schelling G, Kolassa IT. Endocannabinoid concentrations in hair are associated with PTSD symptom severity. Psychoneuroendocrinology. 2016 Feb 12;67:198-206.

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