Microbiota, gastrointestinal infections, low-grade inflammation, and antibiotic therapy in irritable bowel syndrome: An evidence-based review

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http://www.ncbi.nlm.nih.gov/pubmed/24857420

Rev Gastroenterol Mex. 2014 May 22. pii: S0375-0906(14)00031-7. doi: 10.1016/j.rgmx.2014.01.004. [Epub
ahead of print] [Article in Spanish]

Schmulson M, Bielsa MV, Carmona-Sánchez R, Hernández A, López-Colombo A, López Vidal Y, Peláez-Luna M, Remes-Troche JM, Tamayo JL, Valdovinos MA.

Abstract

BACKGROUND:

Post-infectious irritable bowel syndrome (PI-IBS) prevalence, small intestinal bacterial overgrowth (SIBO), altered microbiota, low-grade inflammation, and antibiotic therapy in IBS are all controversial issues.

AIMS:

To conduct an evidence-based review of these factors.

METHODS:

A review of the literature was carried out up to July 2012, with the inclusion of additional articles as far as August 2013, all of which were analyzed through the Oxford Centre for Evidence-Based Medicine (OCEBM) system.

RESULTS:

1.There is greater SIBO probability in IBS when breath tests are performed, but prevalence varies widely (2-84%). 2.The gut microbiota in individuals with IBS is different from…

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