Immunomodulation of mast cells by nutrients

the best compound from food which regulates the mast cells is of course palmitoylethanolamide (PeaPure), but sadly enough the concentration in food is too low, one needs the supplement therefore…but the good news is the absence of side effects and the easiness of using and trying it…step in dose is 3 times 400 mg…dosing higher is possible …

Mastopedia Research Feed

Mol Immunol. 2014 Feb 10. pii: S0161-5890(13)00585-3. doi: 10.1016/j.molimm.2013.12.005. [Epub ahead of print]

Hagenlocher Y, Lorentz A.


In the past decades an increasing prevalence of allergic disorders was observed in industrialized countries. Thus, it is necessary to develop adequate therapeutic and preventive strategies. Many of the conservative strategies possess diverse harmful side effects. Therefore agents with fewer side effects and a better compliance among afflicted patients would be of interest. Especially substances with natural origin acting immunomodulatory on mast cells – the key effector cells of allergic diseases – could be used. Among them there are components of the daily diet such as distinct fatty acids and amino acids as well as a range of secondary plant substances such as carotenoids, flavonoids and spices. These nutritional substances could be applied as nutraceuticals in the therapy of mast cell associated diseases. Many of these substances show inhibitory…

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