Palmitoylethanolamide Versus a Nonsteroidal Anti-Inflammatory Drug in the Treatment of Temporomandibular Joint Inflammatory Pain

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The endogenous nature of PEA and its capacity to act locally and to protect tissues against damage are the premises upon which its therapeutic applications are based:

* First, the lack of side effects allows the therapeutic use of PEA for long periods, and this is particularly important for patients manifesting pain associated with chronic diseases and who are already undergoing several debilitating pharmacological therapies.

* Secondly, the presence of a double therapeutic effect, anti-inflammatory and antinociceptive,47 is particularly important for pathologies presenting chronic inflammatory processes such as TMJ or joint OA that continuously stimulate the somatosensory system and induce allodynia and hyperalgesia.

In conclusion, the results of the present study demonstrate that PEA is effective in reducing TMD- related OA and arthralgia pain, thus suggesting its therapeutic use as an alternative tool to ibuprofen.

Palmitoylethanolamide Versus a Nonsteroidal Anti-Inflammatory Drug in the Treatment of Temporomandibular Joint Inflammatory Pain

Maggiori informazioni su l’essenza del palmitoiletanolamide (PeaPure, Normast)

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