Palmitoylethanolamide: biochemistry, pharmacology and therapeutic use

In February 2013 a number of important articles on PEA were published in a high ranked medical journal. For once in the history of that journal all these articles have been dissiminated for free, as free PDF’s. Here we present some details of the editorial, were PEA is described by Dr S. Skraper, co-worker of Prof. Rita Levi-Montalcini:

Review of Palmitoylethanolamide

Review of Palmitoylethanolamide

Dr Skraper also listed some of the recent clinical results as published in literature:

Clincial trials with palmitoylethanolamide

Clincial trials with palmitoylethanolamide

Here the list of articles with summeries published in the journal:

Measurement of palmitoylethanolamide and other N-acylethanolamines during physiological and pathological conditions.

Balvers MG, Verhoeckx KC, Meijerink J, Wortelboer HM, Witkamp RF.

CNS Neurol Disord Drug Targets. 2013 Feb 1;12(1):23-33.

PMID:

 

23394528

 

[PubMed – in process]

Related citations

Select item 233945276.

Biosynthetic pathways of bioactive N-acylethanolamines in brain.

Tsuboi K, Ikematsu N, Uyama T, Deutsch DG, Tokumura A, Ueda N.

CNS Neurol Disord Drug Targets. 2013 Feb 1;12(1):7-16.

PMID:

 

23394527

 

[PubMed – in process]

Related citations

Select item 233945267.

Neuroglial roots of neurodegenerative diseases: therapeutic potential of palmitoylethanolamide in models of Alzheimer’s disease.

Scuderi C, Steardo L.

CNS Neurol Disord Drug Targets. 2013 Feb 1;12(1):62-9.

PMID:

 

23394526

 

[PubMed – in process]

Related citations

Select item 233945258.

Physiological role of peroxisome proliferator-activated receptors type alpha on dopamine systems.

Melis M, Carta G, Pistis M, Banni S.

CNS Neurol Disord Drug Targets. 2013 Feb 1;12(1):70-7.

PMID:

 

23394525

 

[PubMed – in process]

Related citations

Select item 233945249.

Palmitoylethanolamide reduces formalin-induced neuropathic-like behaviour through spinal glial/microglial phenotypical changes in mice.

Luongo L, Guida F, Boccella S, Bellini G, Gatta L, Rossi F, de Novellis V, Maione S.

CNS Neurol Disord Drug Targets. 2013 Feb 1;12(1):45-54.

PMID:

 

23394524

 

[PubMed – in process]

Related citations

Select item 2339452310.

New insights in mast cell modulation by palmitoylethanolamide.

De Filippis D, Negro L, Vaia M, Cinelli MP, Iuvone T.

CNS Neurol Disord Drug Targets. 2013 Feb 1;12(1):78-83.

PMID:

 

23394523

 

[PubMed – in process]

Related citations

Select item 2339452211.

Effect of diet on tissue levels of palmitoylethanolamide.

Hansen HS.

CNS Neurol Disord Drug Targets. 2013 Feb 1;12(1):17-25.

PMID:

 

23394522

 

[PubMed – in process]

Related citations

Select item 2339452112.

Editorial: palmitoylethanolamide: biochemistry, pharmacology and therapeutic use of a pleiotropic anti-inflammatory lipid mediator.

di Marzo V, Skaper SD.

CNS Neurol Disord Drug Targets. 2013 Feb 1;12(1):4-6. No abstract available.

PMID:

 

23394521

 

[PubMed – in process]

Related citations

Select item 2339452013.

Palmitoylethanolamide in homeostatic and traumatic central nervous system injuries.

Esposito E, Cuzzocrea S.

CNS Neurol Disord Drug Targets. 2013 Feb 1;12(1):55-61.

PMID:

 

23394520

 

[PubMed – in process]

Related citations

Select item 2339451914.

Non-neuronal cell modulation relieves neuropathic pain: efficacy of the endogenous lipidpalmitoylethanolamide.

Bettoni I, Comelli F, Colombo A, Bonfanti P, Costa B.

CNS Neurol Disord Drug Targets. 2013 Feb 1;12(1):34-44.

PMID:

 

23394519

 

[PubMed – in process]

Related citations

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