We quote from
PAIN IN PATIENTS WITH CHRONIC IDIOPATHIC AXONAL POLYNEUROPATHY, by P.G. Erdmann, F.R. van Genderen, L.L. Teunissen, N.C. Notermans, E. Lindeman, A.J.M. van Wijck, N.L.U. van Meeteren, in: European Neurology 2010;64:58-64
Of the 91 patients with CIAP, 63 (69%) reported pain, which had a median duration
of 4.25 years (range, 0–35 years). The median current pain severity on the VAS
was 33 mm, with a median minimal pain severity of 16 mm and median maximum
pain severity of 63 mm; there was considerable variation in the pain scores (Table
1). In total, 12 patients were classified as having severe pain (VAS score >54 mm),
22 moderate pain (VAS score 30–54 mm), and 29 mild pain (VAS score <30)23,24
Sixty-four percent of the patients reported pain of varying severity and 22%
reported pain of constant severity; 14% reported experiencing intermittent pain.
Thirty-nine percent of patients reported exacerbation of pain at night.
Thirty-eight patients with CIAP (42%) were classified as experiencing neuropathic
pain (i.e., as belonging to the NP subgroup or the NP&NNP subgroup)).
Of the 27 patients in the NP subgroup, 14 (52%) experienced pain in the feet and
the lower legs, 10 (37%) experienced pain in the feet, and 3 (11%) experienced
pain in the lower legs; 7 patients (26%) also experienced pain in the hands and 2
(7%) experienced pain in the hands and lower arms.
In total, 69% of the patients
reported experiencing pain, with 30% reporting symmetric distal pain (i.e.,
presumably neuropathic pain), 27% non-neuropathic pain, and 12% a combination
of neuropathic and non-neuropathic pain.