Palmitoylethanolamide reduces iNOS and counteracts inflammation damage

Schermafbeelding 2013-01-07 om 20.20.21

Palmitoylethanolamide protects brain during injury and one of the mechanisms is to inhibit iNOS. Here we see the iNOS in unprotected brain (black) and protected by PEA. iNOS, is involved in immune response, and produces NO as an immune defense mechanism. Hoiwever, NO is a free radical with an unpaired electron. It is the proximate cause of septic shock and may function in autoimmune disease. PEA reduces this damage.

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